The Characterization of Spray Dried Biologics

Spray drying is a leading method for creating dry powders for oral, pulmonary, nasal and injectable dosage forms. This paper explores the assay techniques required to characterize dry powder biologics.

Physical Characterization

Particle size, morphology, moisture and solid-state properties determine performance of dry powders.

Biological Integrity

Assays confirm that structure and activity are preserved through the drying process.

Method Selection

Choosing orthogonal techniques gives a complete picture and supports regulatory submissions.