Advancing Complex Molecules: A Start-to-Finish Guide

This eBook explores pharmaceutical classification models, bio-performance modeling, amorphous solid dispersions, precision particle engineering and first-in-human development, with expert perspectives on improving bioavailability.

Developability Assessment

Early assessment of solubility, permeability, stability and hygroscopicity exposes formulation challenges before they become costly and guides the choice of enabling technologies.

Pharmaceutical Classification Models

The Biopharmaceutics Classification System and Developability Classification System help predict formulation challenges and select suitable technologies.

Amorphous Solid Dispersions

ASDs prepared by spray drying, hot-melt extrusion or co-precipitation are among the most widely used approaches for poorly soluble compounds.

Scale-Up and Commercial Readiness

Careful attention to process parameters, equipment selection and analytical method development prevents late-stage changes and accelerates the path to market.